Kim, Min-Ho Liu, Wei Borjesson, Dori L Curry, Fitz-Roy E Miller, Lloyd S Cheung, Ambrose L Liu, Fu-Tong Isseroff, R Rivkah Simon, Scott I
Published in
The Journal of investigative dermatology
Neutrophil influx is an early inflammatory response that is essential for the clearance of bacteria and cellular debris during cutaneous wounding. A non-invasive real-time fluorescence imaging technique was developed to examine the kinetics of enhanced green fluorescence protein-polymorphonuclear leukocyte (EGFP-PMN) influx within a wound. We hypot...
Chalupa, Allison Koshoffer, Amy Galan, Emily Yu, Lan Liu, Fu-Tong Boissy, Raymond E
Published in
The Journal of investigative dermatology
Galectin-3 is a family member of the carbohydrate-binding proteins widely expressed by many cell types and exhibits multiple cellular functions. We demonstrate that melanocytes express galectin-3, which is predominantly localized to the cell body peripherally along the Golgi zone. Downregulation of galectin-3 in human melanocytes using short hairpi...
Liu, Wei Hsu, Daniel K Chen, Huan-Yuan Yang, Ri-Yao Carraway, Kermit L 3rd Isseroff, Roslyn R Liu, Fu-Tong
Published in
The Journal of investigative dermatology
The EGFR-mediated signaling pathways are important in a variety of cellular processes, including cell migration and wound re-epithelialization. Intracellular trafficking of EGFR is critical for maintaining EGFR surface expression. Galectin-3, a member of an animal lectin family, has been implicated in a number of physiological and pathological proc...
Chen, Hung-Lin Chiang, Po-Cheng Lo, Chia-Hui Lo, Yuan-Hsin Hsu, Daniel K Chen, Huan-Yuan Liu, Fu-Tong
Published in
The Journal of investigative dermatology
Galectin-7, a member of the β-galactoside-binding protein family, is primarily expressed in stratified epithelial cells, including keratinocytes. There is information in the literature suggesting a role for this protein in regulation of keratinocyte survival and growth, but the underlying mechanism remains relatively unknown. Moreover, its expressi...
