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IgE, Mast Cells, and Eosinophils in Atopic Dermatitis

Liu, Fu-Tong Goodarzi, Heidi Chen, Huan-Yuan

Published in Clinical Reviews in Allergy & Immunology

Atopic dermatitis (AD) is a chronic inflammatory skin disease with specific immune and inflammatory mechanisms. Atopy is among the major features of the diagnosis criteria for AD but is not an essential feature. Thus, patients diagnosed with AD can be atopic or non-atopic. This review focuses on the role of IgE, mast cells, and eosinophils in the p...

Mast cells and immunological skin diseases.

Navi, D Saegusa, J Fu-Tong Liu

Published in Clinical Reviews in Allergy & Immunology

Mast cells play an important role in both adaptive and innate immunity, and a large body of literature demonstrates their functions in skin immunity. This article reviews the literature on the role of this cell type in the pathogenesis of a number of immunological skin diseases, including contact dermatitis, atopic dermatitis, immunobullous disease...

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IgE, Mast Cells, and Eosinophils in Atopic Dermatitis

Mast cells and immunological skin diseases.